Long term survival rate following myocardial infarction and the effect of discharged medications on the survival rate

Sahar Bayat, Seyed Saeed Hashemi Nazari, Yadollah Mehrabi, Mohammad Sistanizad


Background: Myocardial infarction  (MI), is considered as an important cause of death and disability. About three - quarters of the deaths caused by heart diseases occur in countries with low or middle economic levels. Evaluation of the effective risk factors and medications and the overlap of their compounds on the long - term survival of patients with myocardial infarction



Methods: In this  retrospective cohort study 21181 patients, hospitalized in coronary care units (CCU) hospitals of Iran enrolled from the MI registry system for the period of 20 March 2013 to 20 March 2014.

Participants were followed up to February 2020 for any cardiovascular disease (CVD) mortality. To evaluate survival rate, difference between groups and to assess factors related to MI death, Kaplan–Meier, Log rank test and Cox Proportional-Hazards Model were used, respectively.


Results: The mean age of patients was 62.10± 13.41.  72.37 % of the patients were men. The rate of survival in the time period in females was less than males. For those patients without the history of coronary diseases, hypertension, and diabetes but with hyperlipidemia and smoking, the 1, 3, 5, and 7-year survival rates were better compared to other patients. The 1, 3, 5, and 7-year survival rates of those in group 6 (Beta blocking agent) were higher compared to other medication groups.


Conclusions: Controlling risk factors can reduce the mortality rate, and the recommendations of doctors and adherence treatment plays an important role in the long - term survival of  Myocardial infarction patients.


Acute Myocardial infarction; survival rate; Cox Proportional-Hazards Model

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