Abstract
Background: Hypertension is elevated blood pressure in the arteries. It is defined as Systolic Blood Pressure (SBP) equal to or above 140 mmHg and/or Diastolic Blood Pressure (DBP) equal to or above 90 mmHg. This study was aimed to identify determinant risk factors of longitudinal change of SBP and DBP with time to first remission of Hypertensive patients.
Study Design: A retrospective cohort study.
Method: We employed descriptive and inferential analysis to explore the determinant risk factors. We applied multivariate joint model to testing the significance association of the possible risk factors.
Result: Of all 369 patients, 235(63.7%) of them had first remission with median survival time of five month. The patients, who had no history of co-morbidity, resided in urban, who took combination of drugs and younger in age had shown shorter first remission time. Similarly, residence, age, treatment, history of Diabetes Mellitus (DM), history of stroke and observation time was determinant risk factors of SBP. On the other hand, age, treatment, history of DM, Chronic Kidney Diseases (CKD) and observation time was identified as determinant risk factors of DBP. The result shows a strong positive association between the change of SBP and DBP (ρ=0.9923). Also, a significant associated between value of SBP and time to first remission (= -0.0693; HR=0.993) was observed.
Conclusion: Having good follow up, controlled comorbidity and taking combination of drugs shows an opportunity in decreasing the blood pressures; consequently, this compels patients to experience the first remission early.